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ACRP Certified Professional Sample Questions:

1. A clinical trial is conducted to measure the effectiveness of music therapy to reduce anxiety in intensive care unit patients. Patients are randomly assigned to receive headphones with music of their choice or headphones with white noise. The group receiving the white noise headphones is considered which type of control group?

A) No treatment
B) Alternate dose
C) Active control
D) Placebo


2. A clinical trial is conducted to test the effect of an investigational drug on cholesterol levels. Statistical analysis will be performed to:

A) Reject the alternative hypothesis that the drug has no effect on cholesterol levels.
B) Reject the null hypothesis that the drug has no effect on cholesterol levels.
C) Fail to reject the alternative hypothesis that the drug has an effect on cholesterol levels.
D) Fail to reject the null hypothesis that the drug has an effect on cholesterol levels.


3. A study protocol must contain which of the following elements?

A) Chemical structure of the IP
B) Description of statistical methods
C) Participant reimbursement details
D) Data management plan


4. A study to determine the effective dose and regimen of a new IP for the treatment of hypothyroidism is considered to be:

A) Phase II
B) Phase IV
C) Phase III
D) Phase I


5. A trial subject was involved in a traffic accident. The emergency room (ER) doctor notifies the investigator that he wants to give the subject a blood transfusion. Blood transfusion is one of the prohibited treatments in the trial. How should the investigator respond?

A) Report this incident immediately to the sponsor and leave the treatment decision to them.
B) Ask the ER doctor not to transfuse blood and consider another treatment compliant with the protocol.
C) Advise the ER doctor to transfuse the blood, and the PI should report this incident to the sponsor.
D) Advise the ER doctor to transfuse blood, and the PI should withdraw the subject from the trial.


Solutions:

Question # 1
Answer: D
Question # 2
Answer: B
Question # 3
Answer: B
Question # 4
Answer: A
Question # 5
Answer: C

ACRP Certified Professional Sample Questions:

1. A clinical trial is conducted to measure the effectiveness of music therapy to reduce anxiety in intensive care unit patients. Patients are randomly assigned to receive headphones with music of their choice or headphones with white noise. The group receiving the white noise headphones is considered which type of control group?

A) No treatment
B) Alternate dose
C) Active control
D) Placebo


2. A clinical trial is conducted to test the effect of an investigational drug on cholesterol levels. Statistical analysis will be performed to:

A) Reject the alternative hypothesis that the drug has no effect on cholesterol levels.
B) Reject the null hypothesis that the drug has no effect on cholesterol levels.
C) Fail to reject the alternative hypothesis that the drug has an effect on cholesterol levels.
D) Fail to reject the null hypothesis that the drug has an effect on cholesterol levels.


3. A study protocol must contain which of the following elements?

A) Chemical structure of the IP
B) Description of statistical methods
C) Participant reimbursement details
D) Data management plan


4. A study to determine the effective dose and regimen of a new IP for the treatment of hypothyroidism is considered to be:

A) Phase II
B) Phase IV
C) Phase III
D) Phase I


5. A trial subject was involved in a traffic accident. The emergency room (ER) doctor notifies the investigator that he wants to give the subject a blood transfusion. Blood transfusion is one of the prohibited treatments in the trial. How should the investigator respond?

A) Report this incident immediately to the sponsor and leave the treatment decision to them.
B) Ask the ER doctor not to transfuse blood and consider another treatment compliant with the protocol.
C) Advise the ER doctor to transfuse the blood, and the PI should report this incident to the sponsor.
D) Advise the ER doctor to transfuse blood, and the PI should withdraw the subject from the trial.


Solutions:

Question # 1
Answer: D
Question # 2
Answer: B
Question # 3
Answer: B
Question # 4
Answer: A
Question # 5
Answer: C

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